Sercon supply isotopically labelled water, enriched in either 18O or D, for energy expenditure and PeT studies

Research into the relationship between energy expenditure, physical activity and body weight is of increasing importance in light of the growing epidemic of obesity and its health-related problems. The doubly labelled water method remains the leading standard for measuring average energy expenditure under free-living conditions. The accurate and reliable measurement obtained using this method is a valuable research tool. TEE (Total Energy Expenditure) of humans or animals can be measured by administering DLW to experimental subjects and following the differential loss of Deuterium and Oxygen-18 isotopes from the body. Sercon provide sterility tested water with both 18O and D labels for energy expenditure studies.

Sercon are global representatives of Taiyo Nippon Sanso’s 18O labelled water, both 10 atom % and 98 atom %, which is used for energy expenditure and PeT studies. We ensure that we supply water of the highest quality at a competitive price for your research requirements. The 18O water is produced using high-purity oxygen. The oxygen is distilled and enriched to more than 97%, and air-separation technology is utilised to produce the isotopically labelled water.
10 Atom % 18O water is used for Total energy expenditure (Tee) measurement as described in Iso8996:2004 (e) 7.2 ergonomics of the thermal environment – Determination of metabolic rate.